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Enzyme and protein polymorphisms were investigated in 218 probands from two population groups in Korea. ALDH 1 phenotypes were determined using hair-root samples after isoelectric focusing. EsD and C3 phenotypes were studied on agarose gel and AcP, 6-PGD and ADA on starch gel by means of coventional electrophoretic techniques. Out of 218 probands tested,about 30% showed a lack of ALDH 1 isozyme, and the frequency obtained has proved to be the lowest of all the Asiatic populations so far examined. The Korean frequency of EsD*2 (0.351-0.365) was close to the values found in Japanese, while it was somewhat higher than other Asiatic populations. Our frequency value of AcP*B (0.782) was similar to that. found in Japanese, but slightly higher than in Chinese it was apparently higher than Europeans but lower compared to African Blacks. The? PGD*C frequency (0.1043) in our samples corresponds well with results reported in other Orientals, while it is significantly higher than those reported from Europeans and African Blacks, the new variant PGD*Korea was not found in the present study. As for the ADA system, ADA*2 frequency (0.043) in this study is similar to that found in Chinese; but slightly higher than that of Japanese, it was somewhat intermediate between those reported from Europeans and African Blacks. Our frequency of C3*S (0.007) corresponds well with the previous observa-tions among different Oriental populations, but it is apparently lower than in Europeans.
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